VOCAL / LEAD — sit it on top, not in front
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1. High-pass             90 Hz for a voice, 150 Hz for a lead synth
2. Subtractive EQ        find the one boxy note between 200-400 Hz and cut 3 dB, narrow
3. Compressor 1          3:1, fast attack, 3 dB gain reduction (control)
4. Compressor 2          2:1, slow attack, 2 dB gain reduction (level)
5. De-ess / tame         -3 dB dynamic band around 6-8 kHz
6. Sends                 dotted-eighth delay at 12%, plate reverb at 15%

Cubase: Frequency -> Compressor -> DeEsser -> sends to PingPongDelay and REVerence.
FL Studio: Fruity Parametric EQ 2 -> Fruity Limiter (COMP) -> Fruity Delay 3 on a send.
Ableton: EQ Eight -> Compressor -> De-Esser (EQ Eight dynamic band) -> returns.
